HKW

Wednesday, September 27, 2006

偉哥之父 路易斯.歇拿奴(Louis Ignarro)教授

1998年諾貝爾生理醫學獎得主路易斯.歇拿奴(Louis Ignarro)教授在香港中文大學的講座內,對年青人有以下的勉勵。

「在學習上,遇到挫折的時候,覺得自己不如人的時候,絕對不要灰心。或許和同儕相比,你必須付出更多更多的努力,才能追及他們的成績─但那又如何?儘管努力去把知識學過來,日後總會有回報的。」

「我自己一向都得比同學們更努力,才能獲得和他們一樣的成績—我不是那種隨意看一遍筆記便能奪A的人,我要比人家更早起床,我星期六也要溫習……但我現在不是取得成果了嗎?」

我只想勉勵人們珍惜在學校的每一刻,我不想嘮叨太多……弄得我像是個家長似的。」

步向科學家之路

和很多好奇心旺盛的小孩一樣,小歇拿奴喜歡把周遭的東西拆散研究。那天,他又向家裏的時鐘施展其「天魔解體大法」……「當時我大概七至八歲吧,媽媽在做飯,我自行把時鐘從牆上拆了下來,為所欲為—媽媽出來看見我的『傑作』:『你在幹什麼?!』並嚇得她當堂尖叫了起來。」
  
類似的故事通常到這裏便完結了。然而歇拿奴揚起眼眉續說:「這時老爸回來,看見災情。他望望那堆廢鐵,又望望我,然後不慌不忙地問:『孩子,你把它拆散了……但你可以把它還原嗎?』」聽到這裏,在場的人都笑了出來。「於是我便把它重組回原狀,掛回牆上。之後它仍能正常運作呢!」

除了機械之外,他也喜歡到林間找些小動物的屍體解剖。「約十歲時,我還試過自製爆竹甚至小規模的炸藥。(試爆成功嗎?)非常成功!」這樣的一個小孩,如果生於現代,準會被懷疑是患了「過度活躍症」吧。
  
他對化學的興趣,則始於父母送他的一份化學實驗教材套。「我完全迷了。我逐個實驗,一步一步跟做,每次成功都讓我很興奮。然後我便自己找相關的化學書看,挑戰其他較高階的教材套……曾經有段時間,我以為自己的志願是製造炸藥和火箭。」
  
歇拿奴對化學的熱情,隨他的成長,與日俱增。念大學期間,他在上了一個藥劑學的科目後,亦對藥物研究產生了興趣。1962年,他在哥倫比亞大學取得藥劑╱化學學士學位;1966年,在明尼蘇達大學取得藥理學╱生理學博士學位。1966至68年,他在美國國家生研究院的化學藥理實驗室從事博士後研究。
  
之後歇拿奴到了Geigy藥廠工作,同時開始他的研究工作。當時他研究的是一種叫「環磷酸鳥」(cyclic GMP)的物質—這是在我們的細胞內,其中一種負責傳遞信息的化合物。後來Geigy和Ciba藥廠合併,歇拿奴則於1973年到杜蘭大學(Tulane University)藥理學系任教。 
 
在其後的研究生涯中,歇拿奴和同事得知,細胞中「環磷酸鳥」的水平是由一種當時被稱為EDRF (endothelium-derived relaxing factor)的神秘物質所決定的。EDRF可提升「環磷酸鳥」的水平,以引發各種生物反應—其中一種是令血管舒張和血壓下降。耐人尋味的是,有實驗的結果顯示,將一氧化氮(nitric oxide,NO)注入細胞,也有同樣的效果。
  
「於是我們問,如果一氧化氮只是單純的空氣污染物,那為何哺乳類動物的細胞會對它作出反應?」歇拿奴說。1985年,他轉到加州大學洛杉磯分校醫學院任教。
  
一連串實驗後,在1986年,歇拿奴和同事們終於證實,之前細胞內身份神秘的EDRF,其真身正是一氧化氮。即一氧化氮除了是空氣中人造的污染物外,原來也是人體內血管自然會製造出來的物質之一。
  
在應用上,由於一氧化氮可以令血管舒張和血壓下降,所以可以作為治療心臟病之用。這些發現讓歇拿奴和另外兩名學者一同奪得1998年的諾貝爾生理醫學獎。


歇拿奴始終認為,他的成功和父母的風格有很大關係。「我的父母雖然教育水平不高,但他們都很聰明,也給了我很多空間……當然也有一點例外:老爸曾對我說,你可以當工程師,可以當律師,唯獨不可以從政。」

歇拿奴笑說:「我的經歷證明了,一個人的成就有多高,並非取決於他父母的成就有多高。」

Monday, September 25, 2006

The God Delusion by Richard Dawkins

About this book

The antireligion wars started by Daniel Dennett and Sam Harris will heat up even more with this salvo from celebrated Oxford biologist Dawkins. For a scientist who criticizes religion for its intolerance, Dawkins has written a surprisingly intolerant book, full of scorn for religion and those who believe. But Dawkins, who gave us the selfish gene, anticipates this criticism. He says it's the scientist and humanist in him that makes him hostile to religions—fundamentalist Christianity and Islam come in for the most opprobrium—that close people's minds to scientific truth, oppress women and abuse children psychologically with the notion of eternal damnation. While Dawkins can be witty, even confirmed atheists who agree with his advocacy of science and vigorous rationalism may have trouble stomaching some of the rhetoric: the biblical Yahweh is "psychotic," Aquinas's proofs of God's existence are "fatuous" and religion generally is "nonsense." The most effective chapters are those in which Dawkins calms down, for instance, drawing on evolution to disprove the ideas behind intelligent design. In other chapters, he attempts to construct a scientific scaffolding for atheism, such as using evolution again to rebut the notion that without God there can be no morality. He insists that religion is a divisive and oppressive force, but he is less convincing in arguing that the world would be better and more peaceful without it. (From Amazon.com)

An extract of interview with the author by Gordy Slack is included here for better illustration of his stance towards religious believe.

For details, please refer to
http://dir.salon.com/story/news/feature/2005/04/30/dawkins/index.html

Once again, evolution is under attack. Are there any questions at all about its validity?
It's often said that because evolution happened in the past, and we didn't see it happen, there is no direct evidence for it. That, of course, is nonsense. It's rather like a detective coming on the scene of a crime, obviously after the crime has been committed, and working out what must have happened by looking at the clues that remain. In the story of evolution, the clues are a billionfold.

There are clues from the distribution of DNA codes throughout the animal and plant kingdoms, of protein sequences, of morphological characters that have been analyzed in great detail. Everything fits with the idea that we have here a simple branching tree. The distribution of species on islands and continents throughout the world is exactly what you'd expect if evolution was a fact. The distribution of fossils in space and in time are exactly what you would expect if evolution were a fact. There are millions of facts all pointing in the same direction and no facts pointing in the wrong direction.

British scientist J.B.S. Haldane, when asked what would constitute evidence against evolution, famously said, "Fossil rabbits in the Precambrian." They've never been found. Nothing like that has ever been found. Evolution could be disproved by such facts. But all the fossils that have been found are in the right place. Of course there are plenty of gaps in the fossil record. There's nothing wrong with that. Why shouldn't there be? We're lucky to have fossils at all. But no fossils have been found in the wrong place, such as to disprove the fact of evolution. Evolution is a fact.

Still, so many people resist believing in evolution. Where does the resistance come from?

It comes, I'm sorry to say, from religion. And from bad religion. You won't find any opposition to the idea of evolution among sophisticated, educated theologians. It comes from an exceedingly retarded, primitive version of religion, which unfortunately is at present undergoing an epidemic in the United States. Not in Europe, not in Britain, but in the United States.

My American friends tell me that you are slipping towards a theocratic Dark Age. Which is very disagreeable for the very large number of educated, intelligent and right-thinking people in America. Unfortunately, at present, it's slightly outnumbered by the ignorant, uneducated people who voted Bush in.

But the broad direction of history is toward enlightenment, and so I think that what America is going through at the moment will prove to be a temporary reverse. I think there is great hope for the future. My advice would be, Don't despair, these things pass.

Believing in God is like believing in a teapot orbiting Mars?
Yes. For a long time it seemed clear to just about everybody that the beauty and elegance of the world seemed to be prima facie evidence for a divine creator. But the philosopher David Hume already realized three centuries ago that this was a bad argument. It leads to an infinite regression. You can't statistically explain improbable things like living creatures by saying that they must have been designed because you're still left to explain the designer, who must be, if anything, an even more statistically improbable and elegant thing. Design can never be an ultimate explanation for anything. It can only be a proximate explanation. A plane or a car is explained by a designer but that's because the designer himself, the engineer, is explained by natural selection.

So why do we insist on believing in God?
From a biological point of view, there are lots of different theories about why we have this extraordinary predisposition to believe in supernatural things. One suggestion is that the child mind is, for very good Darwinian reasons, susceptible to infection the same way a computer is. In order to be useful, a computer has to be programmable, to obey whatever it's told to do. That automatically makes it vulnerable to computer viruses, which are programs that say, "Spread me, copy me, pass me on." Once a viral program gets started, there is nothing to stop it.

Similarly, the child brain is preprogrammed by natural selection to obey and believe what parents and other adults tell it. In general, it's a good thing that child brains should be susceptible to being taught what to do and what to believe by adults. But this necessarily carries the down side that bad ideas, useless ideas, waste of time ideas like rain dances and other religious customs, will also be passed down the generations. The child brain is very susceptible to this kind of infection. And it also spreads sideways by cross infection when a charismatic preacher goes around infecting new minds that were previously uninfected.

You've said that raising children in a religious tradition may even be a form of abuse.
What I think may be abuse is labeling children with religious labels like Catholic child and Muslim child. I find it very odd that in our civilization we're quite happy to speak of a Catholic child that is 4 years old or a Muslim of child that is 4, when these children are much too young to know what they think about the cosmos, life and morality. We wouldn't dream of speaking of a Keynesian child or a Marxist child. And yet, for some reason we make a privileged exception of religion. And, by the way, I think it would also be abuse to talk about an atheist child.

You are working on a new book tentatively called "The God Delusion." Can you explain it?
A delusion is something that people believe in despite a total lack of evidence. Religion is scarcely distinguishable from childhood delusions like the "imaginary friend" and the bogeyman under the bed. Unfortunately, the God delusion possesses adults, and not just a minority of unfortunates in an asylum. The word "delusion" also carries negative connotations, and religion has plenty of those.

What are the dark sides of religion today?
Terrorism in the Middle East, militant Zionism, 9/11, the Northern Ireland "troubles," genocide, which turns out to be "credicide" in Yugoslavia, the subversion of American science education, oppression of women in Saudi Arabia, Afghanistan, and the Roman Catholic Church, which thinks you can't be a valid priest without testicles.

Does religion contribute to the violence of Islamic extremists? Christian extremists?
Of course it does. From the cradle, they are brought up to revere martyrs and to believe they have a fast track to heaven. With their mother's milk they imbibe hatred of heretics, apostates and followers of rival faiths.

I don't wish to suggest it is doctrinal disputes that are motivating the individual soldiers who are doing the killing. What I do suggest is that in places like Northern Ireland, religion was the only available label by which people could indulge in the human weakness for us-or-them wars. When a Protestant murders a Catholic or a Catholic murders a Protestant, they're not playing out doctrinal disagreements about transubstantiation.

What is going on is more like a vendetta. It was one of their lot's grandfathers who killed one of our lot's grandfathers, and so we're getting our revenge. The "their lot" and "our lot" is only defined by religion. In other parts of the world it might be defined by color, or by language, but in so many parts of the world it isn't, it's defined by religion. That's true of the conflicts among Croats and the Serbs and Bosnians -- that's all about religion as labels.

The grotesque massacres in India at the time of partition were between Hindus and Muslims. There was nothing else to distinguish them, they were racially the same. They only identified themselves as "us" and the others as "them" by the fact that some of them were Hindus and some of them were Muslims. That's what the Kashmir dispute is all about. So, yes, I would defend the view that religion is an extremely potent label for hostility. That has always been true and it continues to be true to this day.

How would we be better off without religion?
We'd all be freed to concentrate on the only life we are ever going to have. We'd be free to exult in the privilege -- the remarkable good fortune -- that each one of us enjoys through having been being born. An astronomically overwhelming majority of the people who could be born never will be. You are one of the tiny minority whose number came up. Be thankful that you have a life, and forsake your vain and presumptuous desire for a second one. The world would be a better place if we all had this positive attitude to life. It would also be a better place if morality was all about doing good to others and refraining from hurting them, rather than religion's morbid obsession with private sin and the evils of sexual enjoyment.

Are there environmental costs of a religious worldview?
There are many religious points of view where the conservation of the world is just as important as it is to scientists. But there are certain religious points of view where it is not. In those apocalyptic religions, people actually believe that because they read some dopey prophesy in the book of Revelation, the world is going to come to an end some time soon. People who believe that say, "We don't need to bother about conserving forests or anything else because the end of the world is coming anyway." A few decades ago one would simply have laughed at that. Today you can't laugh. These people are in power.

Is there an emotional side to the intellectual enterprise of exploring the story of life on Earth?
Yes, I strongly feel that. When you meet a scientist who calls himself or herself religious, you'll often find that that's what they mean. You often find that by "religious" they do not mean anything supernatural. They mean precisely the kind of emotional response to the natural world that you've described. Einstein had it very strongly. Unfortunately, he used the word "God" to describe it, which has led to a great deal of misunderstanding. But Einstein had that feeling, I have that feeling, you'll find it in the writings of many scientists. It's a kind of quasi-religious feeling. And there are those who wish to call it religious and who therefore are annoyed when a scientist calls himself an atheist. They think, "No, you believe in this transcendental feeling, you can't be an atheist." That's a confusion of language.

Saturday, September 23, 2006

Philanthropists desperately needed in China

The robust economic growth in China has created an expanding population of middle classes and business tycoons. However, according to a recent survey, the contribution of business sectors in philanthropic activities is far less when compared with the Western counterparts. The discrepancy can be attributed to the differences between the East and West in corporate culture and wealth management.

In many Chinese corporations, the founders make all the necessary arrangement to ensure the smooth transition of the business kingdom to his heir. The wealth of the first generation tycoons is passed to the subsequent generations. However, in most cases, the second generation of tycoons fails to keep the business flourish.

In the West, instead of passing all properties to their heir, it is far more common to see business founders apportioning most of their wealth to philanthropic activities. The recent acts of Warrant Buffet and Bill Gate are vivid examples. The leadership of the business seldom falls on the shoulder of family members.

The idea of corporate social responsibility is quite new to many Chinese tycoons. The rapid expansion of the well-off population widens the gap between the rich and the poor. This lays the seed of fury and social instability in China. If more Chinese tycoons act like their Western counterparts in terms of monetary contribution and determination in philanthropist activities, the under-privileges will taste the fruit of economic growth and the ‘anti-rich’ sentiment in the rural community will be soothed.

Thursday, September 14, 2006

論「九一一陰謀論」

我那個「知識分子」朋友在內地某知識分子雲集的討論區內,發表了一系列頗具爭議的文章,可讀性很高,現列於下:

也许事件已经发生了一段颇长时间,故文章未能在论坛上引起热烈讨论。但事实上,几年以来美国官方对事件的调查几乎毫无寸进,民间对官方说法的怀疑却与日俱增。有民意调查显示,半数以上美国人认为布什政府在事件上有刻意隐瞒或蓄意欺骗公众的嫌疑。不少非主流媒体和民间组织,都极力遁不同渠道搜集资料,从不同角度质疑官方说法的可信性。咱老百姓(真)网友提及的Scholars 911,只是其中较著名民间组织之一。

在九.一一事件上,任何跟官方说法不一致的言论,都被指为“阴谋论”。然而,出现各式各样揣测的真正原因,其实在于许多与案情相关的重要资料,都被列为不能向公众透露的国家机密。此外,官方对那些提出质疑而又有公信力的“异见人士”,采取极不宽容的态度。不久前,University of Wisconsin的一位大学教授Kevin Barrett,就因为公开质疑官方说法,被共和党政客点名批评,结果在国会议员向校方施压下,惨被剥夺教席。

九.一一事件有什么可疑之处?众所周知,在事件发生后不足48小时,布什政府及主流媒体在完全没有任何证据下,便一口咬定拉登及其领导的基地组织,就是事件的幕后的主谋。不过,稍有留意时事的人都应该知道,拉登在恐怖袭击事件发生后的首两年里,一直矢口否认自己是幕后黑手。假如事件真的是由他所策划,为什么要一改以往的作风,不肯直接承认责任?

1998年,当拉登承认策划炸毁美国在肯尼亚和坦桑尼亚使馆,便立即成为了美国的头号通缉犯。难道拉登还会天真地以为,只要坚决否认九.一一惨剧的责任,美国政府就放会过他吗?试想换了你是拉登,既然布什政府己经向全世界宣判自己的死罪,为何不索性将计就计,借机会加以表扬那些劫机者,鼓励更多信众加入恐怖活动,让西方国家永无宁日?

篇幅所限,无意详细验证不同版本“非官方理论”的真伪,只能简单解释我以前曾经提及过的以及我认为可信性较高的论据,请各位关注这宗世纪疑案的朋友,凭大家的判断力和独立思考能力,衡量各种理据和疑点,耐心地抽丝剥茧,作出最合情合理的推测和结论。在《九一一惨剧背后的阴谋》这篇旧作里,我提出的重要疑点之一,是在惨剧发生前金融市场出现的异常现象:

“根据布隆伯格(Bloomberg) 及摩根斯丹利(Morgan Stanley) 等多家大型证卷投资公司所提供的数据显示,在911惨剧发生之前的几个交易日内,在纽约、东京、法兰克福及香港等主要市场上,都突然涌现异常大量的期权淡仓(按:“认沽期权”;put options),而且所针对的几乎都是航空及保险业的股份。故此有专家指出,策划911恐怖袭击的组织,几乎可以肯定是拥有巨额资金的国际“高科技”犯罪集团;像拉登这样活跃于阿富汗山区的游击队,要部署类似的大规模国际投机活动及恐怖袭击实在极为困难。”

由于期货及期权交易客户必须登记有效的户口,美国证券及交易委员会(Securities and Exchange Commission)及联邦调查局(FBI)理应可以凭事发期间的交易纪录顺藤摸瓜,按图索骥,查出相关客户的身份资料。为什么从没听闻这方面的调查有任何进展?为什么国会从没要求公开有关交易的数据?政府内部是否有高层人物牵涉其中?还是另有不可告人的内情?

至于咱老百姓(真)网友谈及世贸中心大楼之内可能早已埋有大量炸药的“猜想”(即所谓“controlled demolition theory”),在网络上的英语讨论区里,向来甚嚣尘上。就我所知,飞机用煤油(kerosene)在燃烧时所产生的高温,一般只有摄氏450度左右,而要令大楼的钢筋熔解,温度至少要在1,500度以上,何况当时大楼受火灾影响的楼层不断冒出黑烟,明显出现氧气不足的现象,因此从物理学角度而言,两座大楼纯粹因为烈火焚烧而倒塌的可能性不太高。

大楼较低的楼层没有受飞机直接撞击,而根据事发当日参与救援行动消防队员的谈话记录,当时两座大楼低层的火势并不猛烈。奇怪的是,在清理大楼倒塌后所产生的瓦砾时,录像显示大楼地基部份竟然出现大片被烧熔钢筋残骸。看过有关纪录片的朋友都知道,大楼倒塌前的一刻不断传出连环爆炸声,是否有人早在大楼各层埋下炸药,也许已经死无对证。不过最让人惊叹不已的奇迹是,大部份飞机残骸都被烧至近乎灰飞烟灭,而劫机者的护照被发现时却几近完好无缺!

更不可思议的是,在两所大楼倒塌7小时之后,同一地段楼高47层的世贸中心第七大楼,在瞬间发生“垂直式急速下塌”的超自然现象。证据显示,第七大楼既没有受飞机撞击,又没有发生严重火灾的迹象,为什么会无缘无故自动倒塌?假如第七大楼倒塌是因为早已被预先埋下炸药,较早前两座大楼倒塌的原因,是否真的是被飞机撞击后发生火灾那么简单?

据德国“Manager Magazine”2001年的报导,犹太籍商人Larry Silverstein在2001年1月,以32亿美元投得世贸中心的业权。值得怀疑的是,当时科网泡沫已经爆破,世贸中心的租值大跌,空置的办工室根本租不出去,而楼宇结构部份又蕴含大量石棉,如要拆卸重建,将牵涉数不清的巨额法律诉讼。为什么Larry Silverstein仍要为这些物业作巨额投保?(www.answers.com上提供的资料说,Larry Silverstein事后获保险公司赔偿合共约50亿美元。另外有报导说,Larry Silverstein承认计划以引爆炸药的方式拆卸第七大楼,世事是否真的如此巧合?)我曾经指出,在九.一一事件上,以以色列政府及相关的犹太激进组织嫌疑最大。首先,发生劫机事件的机场保安,全部都是由一家以色列拥有的集团ICTS负责。此外,据Fox News以及《华盛顿邮报》的报导,美国在2000至2001年期间,共拘捕约200名在美国从事可疑间谍活动的以色列人,其后全数被遣返以色列。在事发当日,五名以色列人因为形迹可疑而被拘捕。根据Fox News的新闻评述员Carl Cameron访问华府高层政府人员的谈话记录,被捕的以色列人经FBI调查,证实是以色列情报组织Mossad的成员。这五名特工明显早有准备,在九.一一事件发生时,于邻近有利位置利用非常完备的录像器材,兴高采烈地拍摄恐怖袭击的全部过程。据悉五人被捕后被交由接受九.一一专案小组调查,但旋即被遣返祖国。

总而言之,官方说法惹人怀疑之处甚多,不能尽录。奈何求证工作困难重重,加上布什政府是事件的间接得益者,一直对事件涉及的许多问题采取保密和高压态度,并与主流媒体合作(多由犹太人操控),开动宣传机器硬销官方说法。基于上述原因,真相是否会有水落石出的机会?于我而言,恐怕并不乐观。

Wednesday, September 06, 2006

在学校学不到的11条准则- -

1. 人生是不公平的,要去适应它。
2. 这世界并不会在意你的自尊。它指望你在自我感觉良好之前先要有所成就。
3. 高中刚毕业你不会一年挣4万美元。你不会成为一个公司的副总裁,并拥有一部装有电话的汽车。这些都要靠努力才能得到。
4. 如果你认为你的老师严厉,等你有了老板再这样想。老板可是没有任期限制的。
5. 做烙牛肉饼的工作并不有损你的尊严。你的祖父母有不同的看法,他们称它为:机遇。
6. 如果你陷入困境,那不是你父母的过错,所以不要发牢骚抱怨我们的错误,要从中吸取教训。
7. 在你出生前,你的父母并不像他们现在这样乏味,他们变成今天这个样子是因为他们一直在为你付账单,给你洗衣服,听你自吹自擂。
8. 学校里成绩的高低好坏,对人生来说还言之过早。
9. 人生不是学期制,人生没有寒暑假。没有哪个雇主有兴趣帮助你寻找自我,请用自己的闲暇做这件事吧。
10. 电视并不是真实的生活。在现实生活中,人们必须得离开咖啡屋去干自己的工作。
11. 善待乏味的人。有可能将来你会为一个乏味的人工作。

NOTICE: 这11条准则盛传是Bill Gates在一次对高中生的演讲中提出的。不过,据我考证,事实并不见得如此。更可信的说法是Charles Sykes给的这11条准则。它著有一本著名的书:
Dumbing down our kids : Why America's children feel good about themselves but can't read, write, or add.》(准则是否是这本书提出,说法不一,我也无从考证。如果有朋友能看到这本书,并愿意帮忙查查,在下感激不尽)。这本出版于1996年的书主要针对高中生和家长,谈了作者对美国的教育制度、方法的看法,批评大于赞同,倡导一种叫做“Outcome Based Education”的教育方法。书我只通过互联网上的零星资料浏览了一点点,不做评论。
关于准则的出处最可信的是来其来自于1996-9-19出版的San Diego Union Tribune,作者就是Charles J. Sykes,文章题目为Some rules kids won't learn in school。但在传播过程中发生了不少的失真,尤其译为中文之后。可以参考:
· http://www.petting-zoo.net/~deadbeef/archive/3534.html
· http://www.truthorfiction.com/rumors/b/billgatesspeech.htm
· http://www.snopes2.com/language/document/liferule.htm

Friday, September 01, 2006

銀業樹的果實

相中的銀業樹果實像什麼?